汪剑波

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个人简介

2012年毕业于中国科学技术大学化学系,获理学博士学位。20129-20137月任职上海药明康德新药开发有限公司药物化学部项目。2013年加入嘉兴大学。2017-2018年于美国密歇根理工大学开展博士后(访问学者)研究,2018-2021于复旦大学开展博士后研究。主要从事精细化工染料的合成和荧光性能研究,以及药物中间体工艺优化工作。主持国家自然科学基金、浙江省自然科学基金项目及浙江省科技厅公益项目等科研项目。指导浙江师范大学、浙江工业大学及浙江理工大学等联培硕士生8名。以第一作者或通讯作者在Angew. Chem. Int. Ed., Sensors   & Actuators: B., Chem. Comm., Talanta, J. Mater.   Chem. B等国际学术期刊上发表研究论文40,授权中国发明专利6项。

 

主持科研项目:

 

1)      浙江省自然科学基金探索项目(LY20B0600092020.01-2022.12,已结题,主持)

2)      中国博士后科学基金(2019M6513642019.04-2021.07,已结题,主持)

3)      国家自然科学基金青年项目(216061022017.01-2019.12,已结题,主持)

4)      浙江省科技厅公益项目(2016C370502016.01-2017.12,已结题,主持)

5)      浙江省自然科学基金青年项目(LQ15B0600052015.01-2017.12,已结题,主持)

6)      浙江省教育厅科研项目(Y201431756, 2014.10-2015.10, 已结题,主持)

发表学术论文(近五年):

1.           Mengyao   Zhao, Weiping Lai, Benhao Li, Tianwen Bai, Chunyan Liu, Yanfei Lin, Shixuan   An, Longhua Guo, Lei Li, Jianbo Wang*, Fan Zhang*. NIR-II Fluorescence Sensor Based on   Steric Hindrance Regulated Molecular Packing for In Vivo Epilepsy   Visualization.  Angew. Chem. Int. Ed. 2024, e202403968.

2.           Qiangmin   Yu, Yanyun Mao, Tianwen Bai*, Tianqing Ye, Zhengyuan Peng, Kan Chen, Longhua   Guo, Lei Li* and Jianbo Wang*. Near-infrared Rhodols-based fluorescent   probe with large Stokes shift for tracking of H2S in food spoilage   and living cells. Spectrochim. Acta A, 2024, 315, 124250.

3.           Shixuan   An, Yanfei Lin*, Tianqing Ye, Tianwen Bai, Danyi He, Longhua Guo, Zhaosheng   Qian, Lei Li, Haiying Liu* and Jianbo Wang*. An   extra-large Stokes shift near-infrared fluorescent probe for specific   detection and imaging of cysteine. Talanta 2024, 267, 125247.

4.           Yanyun   Mao, Qiangmin Yu, Tianqing Ye, Man Xi*, Weiping Lai, Zhixiang Chen, Kan   Chen*, Lei Li, Haiying Liu and Jianbo Wang*.   New Rhodamine-based sensor for high-sensitivity fluorescence tracking of Cys   and simultaneously colorimetric detection of H2S. Spectrochim. Acta A,   2024, 306, 123589.

5.           Shixuan   An, Yanfei Lin, Jianbo Wang*, Tianqing   Ye, Yanyun Mao, Jian Zhang, Longhua Guo, Lei Lib, Zhaosheng Qian* and Haiying   Liu*. Near-infrared mitochondria-targeted fluorescent probe with large Stokes   shift for rapid and sensitive detection of cysteine/homocysteine and its   bioimaging application. Sensors & Actuators: B, 2023, 374, 132799.

6.           Weiping   Lai, Yanfei Lin*, Tianqing Ye, Yating Yu, Hongwei Zhou, Lei Li, Guoliang Mao*   and Jianbo   Wang*. A novel   near-infrared ratiometric fluorescence probe for Hg2+ based on   quinoline-fused rhodamine dye. J Fluoresc, 2023, 33, 1413–1419.

7.           Jiancheng   Wu, Yanfei Lin*, Yating Yu, Yanbo Li, Tianqing Ye, Hongwei Zhou*, Lei Li, Jianbo Wang*.   A highly selective and sensitive fluorescence probe based on Rhodol for   imaging of endogenous peroxynitrite in living cells. Dyes Pigm 2022, 206, 110597.

8.           Mengyao   Zhao#, Jianbo Wang#,*,   Zuhai Lei, Lingfei Lu, Shangfeng Wang, Hongxin Zhang, Benhao Li, Fan Zhang*.   NIR-II pH Sensor with a FRET Adjustable Transition Point for In Situ Dynamic   Tumor Microenvironment Visualization. Angew.   Chem. Int. Ed. 2021, 60, 5091–5095.

9.           Yating   Yu, Jianbo Wang*, Huan Xiang, Linkun Ying, Chenyuan Wu, Hongwei   Zhou*, Haiying Liu*. A new near-infrared ratiometric fluorescent probe based   on quinoline-fused rhodamine dye for sensitive detection of cysteine and   homocysteine in mitochondria. Dyes Pigm 2020, 183, 108710.

10.     Lu Wang, Jianbo Wang*, Shuai Xia, Xinxin   Wang, Yating Yu, Hongwei Zhou*, Haiying Liu*. A FRET-based near-infrared   ratiometric fluorescent probe for detection of mitochondria biothiol. Talanta 2020, 219, 121296.

11.     Shuai Xia, Jianbo Wang*,   Yibin Zhang*, Nick Whisman, Jianheng Bi, Tessa E. Steenwinkel, Shulin Wan,   Jerry Medford, Momoko Tajiri, Rudy L. Luck*, Thomas Werner* and Haiying Liu*.   Ratiometric fluorescent probes based on through-bond energy transfer of   cyanine donors to near-infrared hemicyanine acceptors for mitochondrial pH   detection and monitoring of mitophagy. J. Mater.   Chem. B, 2020, 8, 1603–1615. (back   cover)

12.     Qingqing Wu, Jianlu   Zheng, Wencui Zhang, Jianbo Wang*, Wenlang Liang*, Florian J. Stadler A   new quinoline-derived highly-sensitive fluorescent probe for the detection,   of hydrazine with excellent large-emission-shift ratiometric response. Talanta 2019, 195, 857-864.

13.     Shuai Xia, Mingxi   Fang, Jianbo Wang*, Jianheng   Bi, Wafa Mazi, Yibin Zhang, Rudy L. Luck*, Haiying Liu*. Near-infrared   fluorescent probes with BODIPY donors and rhodamine and merocyanine acceptors   for ratiometric determination of lysosomal pH variance. Sensors & Actuators: B. Chemical, 2019, 294, 1-13.  

14.     Jianbo   Wang*, Shuai Xia, Jianheng   Bi, Yibin Zhang, Mingxi Fang, Rudy L. Luck*, Yanbo Zeng, Tzu-Ho Chen,   Hsien-Ming Lee* and Haiying Liu*. Near-infrared fluorescent probes based on   TBET and FRET rhodamine acceptors with different pKa values for sensitive   ratiometric visualization of pH changes in live cells. J. Mater. Chem. B 2019, 7, 198–209. (back cover)

 

授权专利:

 

1.  一种水溶性香豆素类荧光探针及其制备方法和应用 ZL201611029585.5   2018.10

2.  一种喹啉基近红外罗丹明荧光染料、比率荧光探针及其合成和应用 ZL202010717074.2   2021.10

3.  一种基于荧光共振能量转移检测生物硫醇的近红外比率荧光探针及其制备和应用   ZL202010566667.32022.04

4.  一种氟硼二吡咯类荧光探针、其制备方法及在金离子检测中的应用 ZL202110164306.62022.07

5.  一种用于快速灵敏检测过氧硝酸盐的Rhodol荧光探针及其制备方法和应用;ZL202210844439.7;2023.10

6.  近红外第二窗口检测pH的双通道比率荧光传感器及其制备方法和应用;ZL202210040382.52023.9

 

获奖情况:

1.  2019年嘉兴市自然科学学术奖三等奖

2.  2019年嘉兴学院勤慎青年学者

3.  2016年嘉兴市自然科学学术奖二等奖

4.  指导本科生获得国创项目2项(20192022),浙江省新苗项目1项(2016);指导本科生获得省级竞赛一等奖2项,省级三等奖1项。

 

联系方式:

 

Email: wjb4207@mail.ustc.edu.cn;   wangjianbo@fudan.edu.cn.

 

 

联系方式

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传真:0573-83642282
电子邮件:zjxu@zjxu.edu.cn
学院纪委邮箱:shjw@zjxu.edu.cn

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