周晓聪

来源 :       作者 :       时间 : 2022-07-12     点击数:    打印

                                                                       

7DC63


个人简介

周晓聪,汉族,中共党员,工学博士,皇冠体育官网化

药系讲师。

主讲课程

有机化学,制药分离工程,制药工艺学

研究方向

1、含氟医药、农药及其中间体的合成工艺研究;

2、新型氟烷基化试剂的设计合成与应用研究;

主持项目:

1抗病毒药物替诺福韦合成工艺开发,企业委托项目,负责人,5万, 2021.8-2023.8

2新型氟化试剂的合成工艺及应用研究,企业委托项目,负责人,30万, 2021.12-2023.12

代表论文(近五年):

1.Teruo   Umemoto*, Bin Zhang, Tianhao Zhu, Xiaocong Zhou, Peng Zhang, Song Hu,   Yuanqiang Li. Powerful, thermally stable, one-pot-preparable, and recyclable   electrophilic trifluoromethylating agents: 2,8-difluoro- and   2,3,7,8-tetrafluoro-S-(trifluoromethyl)dibenzothiopheniumSalts. The Journal of Organic Chemistry. 2017 , 82, 7708–7719.

2.     Teruo   Umemoto*, Xiaocong Zhou, Yuanqiang Li. A new version of Umemoto’s reagents: A   three-step one-pot preparation of 2,3,7,8-tetrafluoro-S-(trifluoromethyl)dibenzothiophenium   triflate. Journal of  Fluorine Chemistry.   2019, 26, 109347.

3.   Keke Wang, Hongliang Huang*, Xiaocong Zhou, Qin   Wang, Guijie Li, Haimin Shen, Yuanbin She*, Chongli   Zhong* Highly chemically stable mofs with trifluoromethyl   groups: effect of position of trifluoromethyl groups on chemical stability. Inorganic Chemistry  2019589, 5725–5732.

4. Xiaocong   Zhou, Guijie Li,* Zongzhou Shao, Kun Fang, Hongjun Gao, Yuanqiang Li, Yuanbin   She*. Four-component acyloxy-trifluoromethylation of arylalkenes mediated by   photoredox catalyst. Organic &   Biomolecular Chemistry. 2019 , 17, 24–29.   

5.     Xiaocong   Zhou, Dufen Hu, Xinyi He, Yuanqiang Li, Youqun Chu *, Yuanbin   She*. Practical and efficient synthesis of aryl trifluoromethyl sulfones from   arylsulfonyl chlorides with Umemoto’s reagent II. Tetrahedron Letters.   2020, 61, 151465.

6. Xiang-Rui   Li, Wen-Xin Li, Zhuo-Wen Zhang, Chuanji Shen, Xiaocong Zhou,* Xue-Qiang Chu,   Weidong Rao,*  Zhi-Liang Shen*.Stereoselective synthesis of   fluoroalkylated Z)-alkene via nickel-catalyzed and iron-mediated hydrofluoroalkylation   of alkynes. Org. Chem. Front., 2021, 8, 6377–6383.

7. Renxiang Liu, Xiao-Cong Zhou,   Xin-Yi He, Yuan-Qiang Li*, Weiqin Zheng, Xiu Wang,    Junkai Guo, Chuanfa Ni*, Jinbo Hu*. Org.   Process Res. Dev. 2022,   26, 2, 380–386

 

授权专利:

1. 周晓聪,梅本照雄,李原强,车大庆. 一种溴代吡啶及其衍生物的三氟甲基化工艺,2021. 4. 6,中国,ZL2016112295154.4.

2. 梅本照雄, 张斌, 朱天昊, 周晓聪, 李原强.   S-( 全氟烷基 )- 二苯并噻吩盐及其制备方法, 2019. 9. 6, 中国, ZL201511023299.3.

3. Umemoto Teruo; Zhang Bin; Zhu Tianhao; Zhou   Xiaocong; Li Yuanqiang. Halogenated S-(perfluoroalkyl)dibenzothiophenium   salt and its production methods. 2018. 12.   18, 美国, US   10155739 B2.

 

获奖情况:

 

联系方式:浙江省嘉兴市广穹路899号嘉兴学院梁林校区5号楼521

 

Email: xczhou@zjxu.edu.cn             Tel:

 

 

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